Andromeda X
Monitor protein expression
Overview
Capable of analyzing any protein size in any buffer, including complex biological samples.
Supports 48 parallel measurements with just 10 µl samples each, enabling direct loading from containers without pipetting and accommodating viscous samples up to 50 mPa s-1.
No need for blank/reference samples, filtration, dialysis, or pipetting.
Processes up to 48 samples per run with a daily maximum of 3000 replicates, utilizing the fastest heating rate.
Continuous sample scanning at specific wavelength windows of 650 nm and 670 nm provides dense, high-quality data at 20 points per minute, facilitating the high scanning rate.
Highly sensitive Spectral Shift optics selectively detect your protein of interest in lysate
Spectral Shift
Mix a Nanotemper RED fluorescent label with your
collected lysate containing the protein of interest. The
labeling kits offer a variety of options, including His-tag and Biotinylated site-selective strategies.
Once your protein is labeled, it is subjected to a thermal ramp, during which the fluorescent properties are monitored to detect protein unfolding and expression levels.
Fast screeningProcesses up to 48 samples per run
Wide temperature rangeRanges from 15 to 95°C
Custom heating ramp rate0.1 – 7 °C/min
Low Sample InputWith just 10 µl samples in each measurement
