iconPCR™
World’s First Real-time Thermocycler with 96 individually controlled wells
Overview
The iconPCR™ by n6 is the world’s first individually controlled, plate-based thermocycling technology — a breakthrough in DNA amplification and next-generation sequencing (NGS) workflows.
Featuring 96 distinct thermocycling elements, iconPCR offers unmatched flexibility and precision for a wide range of genomic applications. It enables unique sample preparation capabilities without compromising the high-throughput format essential for modern laboratory workflows.
The iconPCR system is a compact benchtop instrument designed to operate as a stand-alone platform or be seamlessly integrated into automation systems, all while using standard reagents and consumables.
96 independently programmable thermal zones
Each of the 96 wells is a fully isolated thermal zone, allowing exact protocol matching per sample—regardless of input amount or assay type.
Real-Time Feedback Per Well
Real-time fluorescence detection in each independently controlled well enables live monitoring of amplification curves. This feedback powers in-run decision-making, not just post-run analysis.
AutoNorm™
IconPCR dynamically adjusts cycle numbers per well to normalize output concentrations across all samples—without manual input, added reagents, or downstream correction steps
iconPCR Workflow:
- Prepare pre-PCR reaction mix using your standard reagents plus an intercalator of your choice
- Load samples into a standard 96-well optical plate and seal
- Select a protocol and start the run
- IconPCR monitors amplification in real time and automatically adjusts cycles per well
- Remove plate—libraries are normalized and ready to pool or proceed to cleanup
Amplify. Quantify. Normalize. All at Once
Independent well controlOptimal cycling per sample
Real-time per-well feedbackDynamically adjusts cycles during the run
No Proprietary consumablesCompatible with your existing reagents and workflows
Built-in normalizationEliminates pre- and post-PCR quantification and normalization steps
Sequencing-ready output
No individual SPRI cleanupsOne cleanup on the final pool
