Watchmaker Genomics DNA Library Prep Solutions
Overview
DNA library preparation is now routine in most genomics labs, yet challenges around performance, reliability, and scalability persist — especially when working with limited or variable-quality DNA samples. Watchmaker Genomics provides streamlined, flexible workflows for both genomic and epigenomic profiling, designed to handle all sample types while delivering high conversion rates, reduced bias and artifacts, and reproducible results.
Watchmaker DNA Library Prep Kits with Fragmentation
Combine accuracy and scalability for highly sensitive clinical and translational applications, including FFPE analysis
Watchmaker DNA Library Prep Kits
Deliver improved coverage and sequencing economy with fragmented DNA, including cfDNA from liquid biopsies
Watchmaker DNA Library Prep Kits with TAPS+
Enable direct 5mC detection for simultaneous genomic and epigenomic profiling with higher CpG coverage and improved alignment
Simple, automatable workflows for all sample types
Key Highlights
- Achieve robust, high-quality performance from FFPE samples, including preserved methylation profiles for accurate downstream analysis
- Maximize sensitivity with cfDNA, enabling reliable detection of low-frequency variants and 5mC methylation from challenging liquid biopsy inputs
- Minimize sequence bias and artifacts for improved accuracy and sensitivity
- Streamlined, automatable workflows generate sequencing-ready libraries from inputs as low as 500 pg
Reduction in sequence artifacts Improve assay accuracy
Robust error correctionEnable rare mutation detection
Streamlined workflowDeliver PCR-free libraries in under 90 minutes
Robust fragmentationSupport the use of clinically relevant sample
Uniform sequence coverageImproves sequencing efficiency
Highly tunable fragmentationDeliver consistent library sizes between batches
